Exosome isolation services are designed to help researchers obtain high-quality exosomes from various biological samples for further analysis. These services are crucial for applications in biomarker discovery, drug development, and personalized medicine. Here are some key aspects of exosome isolation services:
Sources of Exosomes for Isolation
- Animal Cell-derived Exosomes: Isolated from cells like stem cells, B cells, dendritic cells, and tumor cells. These exosomes are important for studying intercellular communication, immune responses, and disease progression.
- Body Fluid-derived Exosomes: Sourced from plasma, serum, urine, cerebrospinal fluid, and other bodily fluids. These exosomes are valuable for understanding physiological and pathological processes.
- Plant-derived Exosomes: Extracted from various plant sources, these exosomes have potential applications in disease treatment and health care.
- Microorganism-derived Exosomes: Released by microorganisms, these exosomes play roles in microbial communication and pathogenicity.
Our Methods of Isolation
- Ultracentrifugation: A common method that separates exosomes based on their density using high-speed centrifugation.
- Tangential Flow Filtration: A method which uses molecular weight cut off of 100k membrane that removes most of the proteins and lipids.
- Other Methods: Techniques like size-exclusion chromatography, immunoaffinity capture, and polymer-based precipitation are also used to isolate exosomes.
Applications of Isolated Exosomes
- Biomarker Discovery: Exosomes contain valuable biomarkers that can be used for diagnostic purposes.
- Therapeutic Development: Exosomes can carry therapeutic molecules, making them useful in drug delivery and development.
- Research and Analysis: Isolated exosomes are used in various research studies to understand their roles in different biological processes.
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